'The normal course of COPD is punctuated by increasing frequency and Essay

The normal programme of COPD is punctuated by increasing frequency and severity of exacerbations - Essay ExampleExacerbation is a serious wellness condition that could lead to the loss of lung normal functions. (Prince et al., 2004) For this reason, patients that be experiencing exacerbations may be hospitalized and need to go by dint of a long period of recovery.For the purpose of this study, the researcher allow determine and discuss the significance of exacerbations of COPD in terms of its effect on the patients and the health care service providers. With regards to the proper management of exacerbations, the researcher will highlight the available pharmacological and non-pharmacological options for exacerbations.Exacerbations in patients with COPD are usually associated with a major decline in the long-term quality of the patients life and their lung functioning. (Donaldson et al., 2002 Seemungal et al., 1998) Although the etiology and mechanisms behind a severe COPD exacerba tions are not clear, some(prenominal) studies have shown that infections caused by bacteria (White, Gompertz, Stockley, 2003 Sethi and Murphy, 2001) and virus (Rohde et al., 2003 Seemungal and Wedzicha, 2003) are present during an increase frequency of exacerbations.Exacerbations related to COPD are often associated with the increase in airway inflammation related to eosinophilia (Fujimoto et al., 2005 Zhu et al., 2001), neutrophilic (Aaron et al., 2001 Stockley et al., 2000 Sethi et al., 2000), and neutrophils in bronchial biopsies (Qiu et al., 2003). These pointors may commit to the patients dyspnea or difficulty in breathing. In line with this matter, it has been reported that virtually 25% of COPD patients have reported having experienced a profound total body pain. (Lynn et al., 2000)Due to the fact that most of patients with severe COPD may experience exacerbations, some patients may experience anxiety due to their practicable limitations and hunger for air. Some